康乐院士

   

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康乐,男,19594月生,汉族,澳门银河官网网址科学院院士、发展澳门银河官网网址家科学院院士、国际欧亚科学院院士、美国昆虫学会会士、美国内布拉斯加大学荣誉科学博士,国际生态基因学研究的主要领衔科学家。现任河北大学校长、澳门银河官网网址科学院北京生命科学研究院院长。

康乐院士长期从事生态基因组学研究,通过将分子生物学与生态学结合,系统研究动物适应性和表型可塑性。主持国家级重大研究项目多项。重要研究成果发表在Science, Science Advances, Nature Communications, PNAS, Genome Biology, MBE, eLife, PLoS Genetics等国际著名刊物。发表SCI论文160余篇,被国际SCI期刊引用5300余次,是我国生物学和农业领域高被引科学家2014-2018Scopus)。

担任国际昆虫学会执行理事,澳门银河官网网址昆虫学会理事长,澳门银河官网网址科协生命科学联合体理事长,国际生命科学联合会(IUBS)澳门银河官网网址委员会主席、澳门银河官网网址科协全委会、国家基金委全委会委员。1998年被评为国家有突出贡献的专家,获得国务院特殊津贴。1999年获国家自然科学三等奖,2011年获何梁何利生命科学与技术进步奖,2013年获美国昆虫学会国际杰出科学家奖,2015年获谈家桢生命科学成就奖,2016年获全国优秀科技工作者荣誉称号,2017年获国家自然科学奖二等奖,澳门银河官网网址科学院杰出成就奖。2018年获银河网址巨人计划第三批创新团队领军人才称号。

通讯地址:银河网址保定市五四东路180号河北大学

邮政编码:071002

电子邮箱:lkang@hbu.edu.cn

硕士研究生招生专业071010生物化学与分子生物学,

生态基因组研究方向;

博士研究生招生专业:071000生物学,01生物化学与分子生物学

实验室研究方向

生态基因组研究方向:动物对环境的适应性是生命科学领域的重要研究方向。该研究方向利用分子生物学和基因组学为研究手段,在基因组、转录组、翻译组以及表观遗传水平系统研究动物对环境的适应性。侧重以昆虫为模式系统,研究动物的适应性和表型可塑性的分子调控机制,以及昆虫行为的基因调控,为解析动物行为的机制、智能化基础和和发展人类疾病模型提供依据。

主持科研项目(在研)

1. 2018.04-2021.04 银河网址“巨人计划”第三批创新创业团队,河北大学基因表达与DNA修复创新团队项目,200万;

2. 2019.01-2022.12 飞蝗嗅觉吸引行为的神经分子机制,国家自然科学基金面上项目3187230361

3. 2015.01-2019.12 多巴胺代谢相关长非编码RNA调控飞蝗型变可塑性的机理研究,国家自然科学基金重点项目31430023317

4. 2014.07-2019.06 作物病虫害的导向性防控-生物间信息流与行为操纵,澳门银河官网网址科学院战略性先导科技专项(B类)资助,XDB110100005913万;

代表论著

1. Wei, J.N., Shao, W.B., Cao, M.M., Ge, J., Yang, P.C., Chen, L., Wang, X.H., Kang*, L. 2019. Phenylacetonitrile in locusts facilitates an antipredator defense by acting as an olfactory aposematic signal and cyanide precursor. Science Advances, DOI 10.1126/sciadv.aav5495.[PDF]

2. Yang, M.L., Wang, Y.L., Liu, Q., Liu, Z.K., Jiang, F., Wang, H.M., Guo, X.J., Zhang*, J.Z., and Kang*, L. 2018. A β-carotene-binding protein carrying a red pigment regulates body-color transition between green and black in locusts. eLife, 7:e41362.[PDF]

3. Guo, X.J., Ma, Z.Y., Du, B.Z., Li, T., Li, W.D., Xu, L.L., He, J., and Kang*, L. 2018. Dop1 enhances conspecific olfactory attraction by inhibiting miR-9a maturation in locusts. Nature Communications, 9(1): 1193.[PDF]

4. Ding, D., Liu, G.J., Hou, L., Gui, W.Y., Chen*, B., and Kang*, L. 2018. Genetic variation in PTPN1 contributes to metabolic adaptation to high-altitude hypoxia in Tibetan migratory locusts. Nature Communications. 9(1)p.4991. [PDF]

5. Hou L., Yang P.C., Jiang F., Liu Q.  Wang X.H., Kang L. 2017. The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition. eLife, DOI:10.7554/eLife.22526 [PDF]

6. Chen B., Zhang B., Xu L.L., Li Q., Jiang F., Yang P.C., Xu Y.N., Kang L., 2017. Transposable Element-Mediated Balancing Selection at Hsp90 Underlies Embryo Developmental Variation. Molecular Biology and Evolution. doi:10.1093/molbev/msx062 [PDF]

7. Jiang F., Liu Q., Wang Y.L., Zhang J., Wang H.M., Song T.Q., Yang M.L.,  Wang X.H., Kang L. 2017. Comparative genomic analysis of SET-domain family reveals the origin, expansion, and putative function of the arthropod-specific SmydA genes as histone modifiers in insects. GigaScience, DOI: 10.1093/gigascience/gix031  [PDF]

8. He, J., Chen, Q.Q., Wei, Y.Y., Jiang, F., Yang, M.L., Hao, S.G., Guo, X.J., Chen, D.F., Kang, L. 2016. MicroRNA-276 promotes egg hat ching synchrony by upregulating brm in locusts. Proceeding of the National Academy of Sciences of the USA, 113:584-589. [PDF]

9. Yang M.L., Wang Y.L., Jiang F., Song T.Q., Wang H.M., Liu Q, Zhang J., Zhang J.Z., Kang L., 2016. miR-71 and miR-263 Jointly Regulate Target Genes Chitin synthase and Chitinase to Control Locust Molting.  PLoS Genetics  12e1006257. [PDF]

10. Wang, X.H., Kang,L. 2014.Molecular mechanisms of phase change in locusts. Annual Review of Entomology, 59:225-43. [PDF]

11. Wang, X.H., Fang, X.D., Yang, P.C., Jiang, X.T., Jiang, F.,….. Kang, L., 2014. Locust genome sequence provides insight into swarm formation and long-distance flight. Nature Communications, 10.1038/ncomms3957. [PDF]

12. Yang, M.L., Wei, Y.Y., Jiang, F., Wang, Y.L., Guo, X.J., He, J., Kang, L. 2014. MicroRNA-133 Inhibits Behavioral Aggregation by Controlling Dopamine Synthesis in Locusts. PLoS Genetics10(2): e1004206. doi:10.1371/journal.pgen.1004206 [PDF] 

13. Wang, Y.D., Yang, P.C., Cui, F., Kang, L. 2013. Altered Immunity in Crowded Locust Reduced Fungal (Metarhizium anisopliae) Pathogenesis. PLoS Pathogens, DOI:10.1371/journal.ppat.1003102. [PDF]

14. Wei, J.N, Yang, L.H, Ren, Q, Li, CY, Ge, F., Kang, L.2013. Antagonism between plant odors and trichomes affects tritrophic interactions. Plant Cell & Environment, 36, 315-327. [PDF]

15. Cease, AJ, Elser, JJ, Ford, CF, Hao, S., Kang, L, Harrison*, JF. 2012. Heavy livestock grazing promotes locust outbreaks by lowering plant nitrogen content. Science, 335, 467-469. [PDF]

16. Wu, R., Wu, Z.M., Wang, X.H., Yang, P.C., Yu, D., Zhao, C.X., Xu, G.W., and Kang, L. 2012. Metabolomic analysis reveals that carnitines are key regulatory metabolites in phase transition of the locusts. Proceedings of National Academy of Sciences(USA), 109, 3259-3263. [PDF]

17. Ma, ZY, Guo, XJ, Guo, W, Wang, XH, Kang, L. 2011. Modulation of behavioral phase changes of the migratory locust by the catecholamine metabolic pathway. Proceedings of National Academy of Sciences (USA), 108: 3882-3887. [PDF]

18. Guo, W, Wang, XH, Ma, Z.Y., Xue, L., Han, J.Y., Yu, D., and Kang, L. 2011. CSP and takeout genes modulate the switch between attraction and repulsion during behavioral phase change in the migratory locust. PLoS Genetics, 7(2): e1001291, 1-13. [PDF]

19. Wei, J.N., Wang, L.Z., Zhao, J.H., Li, C.Y., Ge, F. and Kang, L., 2011. Ecological trade-offs between jasmonic acid-dependent direct and indirect plant defences in tritrophic interactions. New phytologist, 189: 557–567. [PDF]

20. Zhang, Y., Wang, X.H., and Kang, L., 2011. A k-mer scheme to predict piRNAs and characterize locust piRNAs. Bioinformatics, 27(6)771–776. [PDF] 

21.Kang, L., Chen, B., Wei, J.N. and Liu, T.X., 2009. Roles of Thermal Adaptation and Chemical Ecology in Liriomyza Distribution and Control. Annual Review of Entomology, 54:127-145. [PDF]

22. Wei, Y.Y., Chen, S., Yang P.C., Kang, L., 2009. Characterization and transcriptomes of small RNAs in two phases of locust. Genome Biology, 10:R6l (doi:10.1186/gb-2009-10-1-r6). [PDF]

23. Kang, L., Han, X.G., Zhang, Z.B. and Sun, O. J., 2007, Grassland ecosystems in China: Review of current knowledge and research advancement. Philos. Trans. Roy. Soc., 362:997-1008. [PDF] 

24.Kang, L., Chen, X.Y., Zhou, Y., Zheng, W., Li R.Q., Wang, J. and Yu, J. 2004. The analysis of large-scale gene expression correlated to the phase changes of the migratory locust.Proceeding of the National Academy of Sciences of the USA, 101: 17611-17615. [PDF]

25.生态基因组学,康乐主编,2019,北京:科学出版社,付印中


 

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